Selected Publications
A lateral signalling pathway coordinates shape volatility during cell migration
Zhang, L., Luga, V., Armitage, S.K., Musiol, M., Won, A., Yip, C.M., Plotnikov, S.V., Wrana, J.L. (2016). Nat Commun. 7, 11714. PMID: 27226243
YAP-dependent reprogramming of Lgr5(+) stem cells drives intestinal regeneration and cancer
Gregorieff, A., Liu, Y., Inanalou, M.R., Khomchuk, Y. and Wrana, J.L. (2015). Nature 526, 715-8. PMID: 26503053
PTEN regulates cilia through Dishevelled
Shnitsar, I., Bashkurov, M., Masson, G.R., Ogunjimi, A.A., Mosessian, S., Cabeza, E.A., Hirsch, C.L., Trcka, D., Gish, G., Jiao, J., Wu, H., Winklbauer, R., Williams, R., Pelletier, L., Wrana, J.L.#, Barrios-Rodiles, M.# (2015). Nat. Commun. 6, 8388. (#co-corresponding) PMID: 26399523
Myc and SAGA Rewire an Alternative Splicing Network During Early Somatic Cell Reprogramming
Hirsch, C.L.*, Coban Akdemir, Z.*, Wang, L., Jayakumaran, G., Trcka, D., Weiss, A., Hernandez, J.J., Pan, Q., Han, H., Xu, X., Xia, Z., Salinger, A.P., Wilson, M., Vizeacoumar, F., Datti, A., Li, W., Cooney, A.J., Barton, M.C., Blencowe, B.J., Wrana, J.L.#, Dent, S.Y. # (2015). Gen. Dev., 29, 803-816. (*co-first, #co-corresponding) PMID: 25877919
Switch Enhancers Interpret TGF-β and Hippo Signaling to Control Cell Fate in Human Embryonic Stem Cells
Beyer, T.A., Weiss, A., Khomchuk, Y., Huang, K., Ogunjimi, A.A., Varelas, X., Wrana, J.L. (2013).Beyer, T.A., Weiss, A., Khomchuk, Y., Huang, K., Ogunjimi, A.A., Varelas, X., Wrana, J.L. (2013). Cell Reports, 26, 1611-1624.
Exosomes mediate stromal mobilization of autocrine Wnt-PCP signaling in breast cancer cell motility
Luga, V. *, Zhang, L.*, Viloria-Petit, A., Ogunjimi, A., Inanlou, M., Chiu, E., Nasser Hosein, A., Buchanan, M., Basik, M. and Wrana, J.L. (2012). Cell, 151, 1542-1556.
A late transition in somatic cell reprogramming requires regulators distinct from the pluripotency network
Golipour, A. *, David, L. *, Liu, Y., Jayakumaran, G., Hirsch, C., Trcka, D., and Wrana, J.L. (2012). Cell Stem Cell, 11, 769-782. *co-first. PMID: 23217423
Tissue specific alternative splicing remodels protein-protein interaction networks
Ellis, J.D.*, Barrios-Rodiles, M.*, Colak, R., Irimia, M., Kim, T., Calarco, J.A., Wang, X., Pan, Q., O'Hanlon, D., Kim, P.M., Wrana, J.L.# and Blencowe, B.# (2012). Mol Cell, 46, 884-892.